Diagnostic Techniques of Soil-Transmitted Helminths: Impact on Control Measures

Diagnostic tools for soil-transmitted helminths control and elimination programs: A pathway for diagnostic product development

Soil-Transmitted Helminths: The Neglected Parasites

Soil-transmitted helminth (STH) infections are still considered to be the most prevalent infections of humankind. STH, traditionally endemic in rural areas, are increasingly becoming a public health concern in urban slums of cities in tropical and subtropical developing countries in Southeast Asia, sub-Saharan Africa and Central and South America. These helminths, Ascaris lumbricoides, hookworm...

Molecular Diagnostics for Soil-Transmitted Helminths

Historically, the diagnosis of soil-transmitted helminths (STHs) (e.g., Strongyloides stercoralis, Trichuris trichiura, Ancylostoma duodenale, Necator americanus, and Ascaris lumbricoides) has relied on often-insensitive microscopy techniques. Over the past several years, there has been an effort to use molecular diagnostics, particularly quantitative polymerase chain reaction (qPCR), to detect...

Recombinant subunit vaccines for soil-transmitted helminths

Soil-transmitted helminths (STHs) collectively infect one fourth of all human beings, and the majority of livestock in the developing world. These gastrointestinal nematodes are the most important parasites on earth with regard to their prevalence in humans and livestock. Current anthelmintic drugs are losing their efficacies due to increasing drug resistance, particularly in STHs of livestock ...

Methods for Quantification of Soil-Transmitted Helminths in Environmental Media: Current Techniques and Recent Advances.

Limiting the environmental transmission of soil-transmitted helminths (STHs), which infect 1.5 billion people worldwide, will require sensitive, reliable, and cost-effective methods to detect and quantify STHs in the environment. We review the state-of-the-art of STH quantification in soil, biosolids, water, produce, and vegetation with regard to four major methodological issues: environmental ...